I don't think so. A movie that amazing doesn't need a sequel. I can watch it over and over again like it's the first time. Besides, the story ended...what would it be about?
As much as I loved the first movie, I just have to say no. The movie ended many years later and I think that even if that ending was very bittersweet it was perfect just the way it ended :')
I hope that Tim Burton who is Johnny's Great Friend and who wants Winona and Johnny back together that he does make Edward Scissorhands so that indeed they get back together in real life.