And probably Isaac because of everything he's been through.

I think all of them have been through a lot...

& Isaac too.

He didn't really have support system since his whole family died and there was that thing with Paige. Same with Isaac but to a lesser degree

HANDS DOWN!!!

Or stiles and Allison

He inadvertently killed Paige, he was basically child molested by Kate Argent, he thought his whole family died in a fire, Laura was murdered and he had to bury her body, Scott won't return the love, his uncle came back and tried to murder him, his girlfriend was a psychopathic druid, he found Erica's dead body, he unintentionally murdered Boyd, he turned Jackson into a kanima, etc.
Pretty sure it's an inside joke to make everything terrible happen to Derek.

Pretty obvious

all of them are emotionally damaged they've been through a lot my first choice is Derek my second choice would be Isaac he has been through a lot too he lost his family his dad his been abused by his father u know that's a lot for a teenage boy to handle Isaac had a hard life and he is so nice funny and cute it's not fair some of the characters like Allyson lost their mom or dad well Isaac lost all of his family his mom and dad

Derek

He lost his family after faling in love with a hunter.
Had to Kill his uncle after finding out he has been the alpha.
Was hunted by the police for a crime he wanted to prevent (High School Battle)
Feld in love with the Darach

then Isaac.